Over time this small amount of light chain has formed amyloid fibrils in the kidneys that have caused the renal damage and proteinuria. The most common biclonal gammopathy was igg kappa igg lambda followed by igg kappa igm lambda. Using assays for monoclonal m proteins electrophoresis immunofixation and kappa lambda free light chains flcs we determined longitudinally the prevalence of mgus and characterized patterns of monoclonal immunoglobulin abnormalities prior to mm diagnosis.
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